Microbiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Microbiology 142 (1996), 3211-3218
This Article
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Karos, M.
Right arrow Articles by Fischer, R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Karos, M.
Right arrow Articles by Fischer, R.
Agricola
Right arrow Articles by Karos, M.
Right arrow Articles by Fischer, R.

microbiology, Vol 142, 3211-3218, Copyright © 1996 by Society for General Microbiology

ARTICLES

hymA (hypha-like metulae), a new developmental mutant of Aspergillus nidulans

M Karos and R Fischer
Laboratorium fur Mikrobiologie, Philipps-Universitat Marburg, Germany.

Asexual fruiting body development in Aspergillus nidulans requires a precise spatial and temporal coordinated expression of many genes. Insertional mutagenesis was used to isolate and characterize a new mutant of A. nidulans in which hyphal growth was slightly reduced and conidiophore development was specifically blocked at the metula stage. In contrast to the uninucleate metulae of the wild-type, in the mutant these structures were elongated, multinucleate and septate. Further differentiation and production of phialides by a budding-like process was not observed. The mutant metulae thus resembled hyphae rather than metulae and the gene was therefore named hypha-like metulae (hymA). The hymA gene was mapped to linkage group VI. The integrated vector was rescued with border sequences from the integration site. The border sequences were used to isolate a cosmid from a wild-type library which was subcloned to a 5 kb fragment able to complement the mutation in trans. This fragment encoded a 1.8 kb transcript expressed in hyphae and throughout development. It is proposed that hymA is involved in budding processes, and is required for the formation of metulae and for their further differentiation.


This article has been cited by other articles:


Home page
 Mol. Biol. CellHome page
F. J. Walton, J. Heitman, and A. Idnurm
Conserved Elements of the RAM Signaling Pathway Establish Cell Polarity in the Basidiomycete Cryptococcus neoformans in a Divergent Fashion from Other Fungi
Mol. Biol. Cell, September 1, 2006; 17(9): 3768 - 3780.
[Abstract] [Full Text] [PDF]

Home page
 Appl. Environ. Microbiol.Home page
M. Brock
Generation and Phenotypic Characterization of Aspergillus nidulans Methylisocitrate Lyase Deletion Mutants: Methylisocitrate Inhibits Growth and Conidiation
Appl. Envir. Microbiol., September 1, 2005; 71(9): 5465 - 5475.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
N. Schier, R. Liese, and R. Fischer
A Pcl-Like Cyclin of Aspergillus nidulans Is Transcriptionally Activated by Developmental Regulators and Is Involved in Sporulation
Mol. Cell. Biol., June 15, 2001; 21(12): 4075 - 4088.
[Abstract] [Full Text]

Home page
 GeneticsHome page
R. A. Prade, P. Ayoubi, S. Krishnan, S. Macwana, and H. Russell
Accumulation of Stress and Inducer-Dependent Plant-Cell-Wall-Degrading Enzymes During Asexual Development in Aspergillus nidulans
Genetics, March 1, 2001; 157(3): 957 - 967.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
INT J SYST EVOL MICROBIOL MICROBIOLOGY J GEN VIROL
J MED MICROBIOL ALL SGM JOURNALS
Copyright © 1996 Society for General Microbiology.