HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Dziadek, J. Articles by McFadden, J. J. Search for Related Content PubMed PubMed Citation Articles by Dziadek, J. Articles by McFadden, J. J. Agricola Articles by Dziadek, J. Articles by McFadden, J. J.

IS990, a new species-specific insertion-sequence-related element of the Mycobacterium tuberculosis complex

¹Centre for Microbiology and Virology, Polish Academy of Sciences, Lodowa 106, 93-232 Lód, Poland
²Department of Genetics of Microorganisms, University of Lód, Banacha 12/16, 93–237 Lód, Poland
³Molecular Microbiology Group, School of Biological Sciences, University of Surrey, Guildford GU2 5XH, UK

ABSTRACT

Summary: The structure and distribution of IS990, a new Mycobacterium tuberculosis DNA sequence with homology to characterized insertion sequences (ISs), were investigated. IS990 was related to IS elements of the IS3 family and was present as a single copy in all 21 investigated M. tuberculosis strains, two Mycobacterium bovis strains and two M. bovis BCG strains. The sequence appears to be specific for the M. tuberculosis complex. The element carries two frameshift mutations and appears to be defective.

Author for correspondence: J. Dziadek. Tel: +48 42 491228. Fax: +48 42 491633. e-mail: jdziadek@wirus.cmiwpan.lodz.pl