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Microbiology 144 (1998), 589-591
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microbiology, Vol 144, 589-591, Copyright © 1998 by Society for General Microbiology

ARTICLES

Inteins in mycobacterial GyrA are a taxonomic character

P Sander, F Alcaide, I Richter, K Frischkorn, E Tortoli, B Springer, A Telenti and EC Bottger
Institut fur Medizinische Mikrobiologie, Medizinische Hochschule Hannover, Germany.

The A subunit of DNA gyrase in mycobacteria is frequently subjected to splicing events as its gene, gyrA, harbours an insertion encoding an intein. Investigation of a number of different isolates of Mycobacterium kansasii, Mycobacterium malmoense, Mycobacterium marinum, Mycobacterium ulcerans and Mycobacterium xenopi demonstrated that the presence of GyrA inteins is not random but a taxonomic character specific for a given taxon at a species or subspecies level.


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