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Microbiology 144 (1998), 801-805; DOI  10.1099/00221287-144-3-801
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A 28 kbp segment from the spoVM region of the Bacillus subtilis 168 genome

David Foulger and Jeffery Errington

Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK

ABSTRACT

The sequence of a 28 kbp segment of DNA surrounding the spoVM gene of Bacillus subtilis 168 (lying at approximately 145° on the standard genetic map) has been determined. The region contains 27 ORFs, a number of which have predicted products significantly similar to proteins in sequence databases, particularly to proteins involved in macromolecular synthesis of nucleic acids, proteins and phospholipids. A pair of closely linked genes encode a likely serine protein phosphatase and a serine protein kinase, respectively. Such proteins play important regulatory roles in eukaryotic cells but are rare in prokaryotes.

Author for correspondence: Jeff Errington. Tel: + 44 1865 275561. Fax: +44 1865 275556. e-mail: erring@molbiol.ox.ac.uk

Keywords: Bacillus subtilis, spoVM




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