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Supplementary data

Improved annotation of conjugated bile acid hydrolase superfamily members in Gram-positive bacteria, by J. M. Lambert, R. J. Siezen, W. M. de Vos and M. Kleerebezem

Microbiology vol. 154, part 8, pp. 2492-2500

Fig. S1. (a) CLUSTAL_X alignment of sequences in the Bsh cluster. (b) CLUSTAL_X alignment of sequences in the Pva cluster. For clarity, one representative sequence is shown when sequences of different strains of the same organism are identical or nearly identical. Black arrowheads indicate catalytic residues; grey arrowheads indicate binding-pocket residues.

Table S1. Annotation of Gram-positive CBAH superfamily members in the phylogenetic tree.

Supplementary material SL1. HMM motifs for Bsh and Pva are available as text files.

Supplementary material SL2. Results of search in sequenced genomes with HMMs for Bsh and Pva, respectively, sorted by the score for either of the HMMs, is available as an Excel file.

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