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Front cover illustration: Fluorescence micrograph illustrating Tir focusing (green fluorescence) beneath intimately attached enteropathogenic Escherichia coli (EPEC) bacteria (blue fluorescence) following EPEC infection of red blood cell monolayers (red fluorescence). Courtesy S. Knutton, Institute of Child Health, University of Birmingham. See the paper by Shaw et al., pp. 1355-1365.