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Front cover illustration

Transmission electron micrograph of Treponema isolated from a bovine digital dermatitis lesion. The fixation treatment has resulted in rupture of the outer membrane, releasing the periplasmic flagella from their tight association with the cytoplasmic cylinder. Photo courtesy of W. A. Cooley (Veterinary Laboratories Agency), A. M. Edwards (University of Bristol) and R. W. Vowles (University of Bristol). See the paper by Edwards et al. on pp. 1083-1093.