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Front cover illustration

Localization of translocated effector protein SopD2 during Salmonella infection. HeLa cells transfected with GFP (green) were infected with Salmonella enterica serovar Typhimurium expressing haemagglutin-tagged effector protein SopD2 (red) that colocalizes with LAMP-1⁺ compartments (blue). Merged image shown at bottom, with colocalization of SopD2 and LAMP-1 shown in pink. Images courtesy Dr Jason Szeto, Hospital for Sick Children, Toronto, Ontario, M5G 1X8, Canada. See the paper by Brown et al. in this issue, pp. 2323-2343.