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Front cover illustration

Four-day-old biofilms of gfp-tagged PAO1 grown in FAB medium were either not treated (top), treated with ciprofloxacin (middle) or treated with EDTA (bottom), after which they were stained with propidium iodide and images were acquired by CLSM. Live cells appear green and dead cells appear yellow or red. The central images show horizontal optical sections, and the flanking pictures show vertical optical sections. Images courtesy Tim Tolker-Nielsen, Centre for Biomedical Microbiology, BioCentrum-DTU, The Technical University of Denmark, Lyngby, Denmark. See the paper by Yang et al. in this issue, pp. 1318-1328.