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Front cover illustration

CLSM micrographs of an in situ oral biofilm, showing the microbial colonization pattern after 12 h in two individuals. Biofilms were stained simultaneously with all-bacterium-specific probe EUB338, Streptococcus-specific probe STR405 and Actinomyces naeslundii-specific probe ACT476. Green (yellow), blue (purple) and red represent streptococci, A. naeslundii and the remaining bacteria, respectively. Images courtesy Irene Dige, Department of Dental Pathology, Operative Dentistry and Endodontics, School of Dentistry, Aarhus University, Denmark. See the paper by Dige et al. in this issue, pp. 2116–2126.